The RLS Foundation is now accepting Letters of Intent for projects that promote research to understand RLS. Deadline for submission is January 24, 2025. The primary research priorities this year are:

• Augmentation: Identifying who is at risk for developing augmentation (e.g. through genetic markers, iron status, or other at-risk clinical phenotypes) and who is lower risk, to understand if there is a subset of RLS patients who can be more safely treated with dopamine agonists long-term.
• Therapeutics: Elucidate the mechanisms involved in the therapeutic and unwanted side effects, (e.g., augmentation) of RLS drugs, novel therapeutics (i.e. medical cannabis) and advance knowledge toward development of more durable treatments.
• Disease risk and expression: Elucidate genetic, epigenetic, biologic factors associations with disease risk or with different RLS phenotypes.
• Other topics: Other research areas accepted for funding consideration.

RLS Foundation Research Grant Policies and Application Procedures.

Support the Success of the RLS Research Grant Program

Thanks to generous donations from individuals in the RLS community, the Foundation has funded over $2 million in competitive research grants for the study of RLS since 1997. Every donation makes a real difference in our understanding of the disease, leading us one step closer to a cure. Consider making a donation to the RLS Foundation research program today!

Please read about our most recent grantees and all the exciting research that supporters like you have made possible! We THANK YOU!